Etoposide Injection

Etoposide Injection

Etoposide Injection

Our Etoposide injection is formulated using balanced chemical composition under controlled processing system. Etoposide injection is used to treat Small Cell Lung Cancer (SCLC) and cancer of the testicles and. It is also sometimes used to treat some other kinds of cancer like malignant lymphomas, acute leukaemias, and trophoblastic diseases. Etoposide impairs DNA synthesis at the premitotic stage of cell division which may lead to apoptosis of the cancer cell.

Precautions

Before using a medicine, it is very important to evaluate the risk of medicine along with its therapeutic benefits. Discuss all the things with doctor in detail.

Contraindications

Use of this medicine is contraindicated if one has severe infection, low amount of albumin proteins in the blood, excess body acid, decreased function of bone marrow, anemia, decreased blood platelets, severely decreased platelets, decreased white blood cells, decreased neutrophils a type of white blood cell, acute hemorrhage, interstitial pneumonitis, lung fibrosis, pregnancy, nursing mothers, moderate to severe kidney impairment, severely decreased levels of neutrophils in the blood.

Side Effects

Visit your doctor immediately if you experience these symptoms- blood in the urine or stools, chest pain, shortness of breath, black, tarry stools, bleeding gums, chills, cough, fever, painful or difficult urination, pale skin, swollen glands, unusual bleeding or bruising etc.




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Contraindications

Use of this medicine is contraindicated in pregnancy, lactation hypersensitivity, renal impairment etc.

Side Effects

Contact with your doctor if you observe adverse effects like nephrotoxicity, nausea, vomiting, tinnitus, deafness, neuropathy, electrolyte imbalance etc.

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Key points:

 

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Di Sodium Pamidronate Injection

It is a bone resorption inhibitor.

Composition :

15mg, 30mg, 60mg, 90mg

Indications :

Hypercalcaemia of malignancy, Paget's disease, Osteolytic bone metastasis of breast cancer, and Osteolytic lesions of multiple myeloma.

Contraindications :

Patients with clinically significant hypersensitivity to pamidronate or other biphosphonates.

Safety Profile :

Standard hypercalcemia related metabolic parameters such as serum levels of calcium, phosphate, magnesium and potassium should be carefully monitored.

Adverse Effects :

Fluid overload, generalized pain, Hypertension, abdominal pain, anorexia, constipation, nausea, vomiting, urinary tract infection, bone pain, anaemia, hypophosphatemia.

Dosage :

Paget's disease - 60mg by slow iv infusion at a rate of 15mg/hour, optimal dosing regimen adjusted individually according to response.
Hypercalcaemia of malignancy : Slow iv infusion at a rate of 60 mg/hour dose adjusted according to initial plasma calcium concentration : 30mg when plasma calcium is below 3.00 mmol/L, 30-60mg when plasma calcium 3.0-3.5 mmol/L, 60-90 mg when plasma calcium 3.5-40 mmol/L, 90 mg when plasma calcium is above 4.0 mmol/L Repeat dose every 2-3 weeks as necessary.
Bone metastasIs : Slow iv infusion 2 hours in breast cancer, 4 hours in multiple myeloma, 90mg every 3-4 weeks.

Purity :

Not less than 99%.

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