Epirubicin Injection

Epirubicin Injection

Epirubicin Injection

Epirubicin injection has strong anti tumor action by interfering with the synthesis and function of DNA. The given injection is used to treat cancers of breast, lungs, ovaries, lymph system and stomach. Epirubicin is an antineoplastic in the anthracycline class which prevents abnormal growth of tissues.

Precautions for Epirubicin Injection

This injection is to be administered only under the supervision of your doctor. Epirubicin should be injected slowly into a vein. Do not inject into a muscle or under the skin. If this medication by coincidence leaks into the skin/muscle around the injection site, it may cause serious damage. Tell your doctor without delay if you observe redness, pain or swelling at or near the injection site.

Contraindications for Epirubicin Injection

Use of this medicine should be avoided in those are allergic to epirubicin or to any of the ingredients of the medication, allergic to other anthracycline-type medications like doxorubicin, breast-feeding, recent heart attack, heart failure, irregular heart rhythm, severe heart disease, severe liver impairment.

Pharmacological Action of

Epirubicin forms a complex with DNA by intercalation of its planar rings between nucleotide base pairs, with consequent inhibition of nucleic acid (DNA and RNA) and protein synthesis.Such intercalation triggers DNA cleavage by topoisomerase II, resulting in cytocidal activity. Epirubicin also inhibits DNA helicase activity, preventing the enzymatic separation of double-stranded DNA and interfering with replication and transcription




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Etoposide Injection

Etoposide Injection

Etoposide Injection

Our Etoposide injection is formulated using balanced chemical composition under controlled processing system. Etoposide injection is used to treat Small Cell Lung Cancer (SCLC) and cancer of the testicles and. It is also sometimes used to treat some other kinds of cancer like malignant lymphomas, acute leukaemias, and trophoblastic diseases. Etoposide impairs DNA synthesis at the premitotic stage of cell division which may lead to apoptosis of the cancer cell.

Precautions

Before using a medicine, it is very important to evaluate the risk of medicine along with its therapeutic benefits. Discuss all the things with doctor in detail.

Contraindications

Use of this medicine is contraindicated if one has severe infection, low amount of albumin proteins in the blood, excess body acid, decreased function of bone marrow, anemia, decreased blood platelets, severely decreased platelets, decreased white blood cells, decreased neutrophils a type of white blood cell, acute hemorrhage, interstitial pneumonitis, lung fibrosis, pregnancy, nursing mothers, moderate to severe kidney impairment, severely decreased levels of neutrophils in the blood.

Side Effects

Visit your doctor immediately if you experience these symptoms- blood in the urine or stools, chest pain, shortness of breath, black, tarry stools, bleeding gums, chills, cough, fever, painful or difficult urination, pale skin, swollen glands, unusual bleeding or bruising etc.

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Di Sodium Pamidronate Injections

Di Sodium Pamidronate Injections

Having enormous experience in this domain, we are successfully engrossed in providing high grade Di Sodium Pamidronate Injection. This injection is formulated with the help of our experienced professionals by utilizing advanced methodology at our well-maintained premises. Known for precise composition, it is injected into patient’s vein for treating high calcium levels or hypercalcemia as well as bone problems. We provide the offered Di Sodium Pamidronate Injection in hygienic packaging at cost effective prices.

Key points:

 

Quick results Enhanced shelf life Highly effective Balanced chemical composition 

 

Di Sodium Pamidronate Injection

It is a bone resorption inhibitor.

Composition :

15mg, 30mg, 60mg, 90mg

Indications :

Hypercalcaemia of malignancy, Paget's disease, Osteolytic bone metastasis of breast cancer, and Osteolytic lesions of multiple myeloma.

Contraindications :

Patients with clinically significant hypersensitivity to pamidronate or other biphosphonates.

Safety Profile :

Standard hypercalcemia related metabolic parameters such as serum levels of calcium, phosphate, magnesium and potassium should be carefully monitored.

Adverse Effects :

Fluid overload, generalized pain, Hypertension, abdominal pain, anorexia, constipation, nausea, vomiting, urinary tract infection, bone pain, anaemia, hypophosphatemia.

Dosage :

Paget's disease - 60mg by slow iv infusion at a rate of 15mg/hour, optimal dosing regimen adjusted individually according to response.
Hypercalcaemia of malignancy : Slow iv infusion at a rate of 60 mg/hour dose adjusted according to initial plasma calcium concentration : 30mg when plasma calcium is below 3.00 mmol/L, 30-60mg when plasma calcium 3.0-3.5 mmol/L, 60-90 mg when plasma calcium 3.5-40 mmol/L, 90 mg when plasma calcium is above 4.0 mmol/L Repeat dose every 2-3 weeks as necessary.
Bone metastasIs : Slow iv infusion 2 hours in breast cancer, 4 hours in multiple myeloma, 90mg every 3-4 weeks.

Purity :

Not less than 99%.

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Effective Cancer Treatment - Dactinomycin Injections

Effective Cancer Treatment - Dactinomycin Injections

Dactinomycin Injection

With the use of modern methodology, this injection is formulated by a team of proficient professionals at our well-resourced premises. Dactinomycin Injection is an anticancer medication that interferes with growth and spread of cancer cells in the body. It is used to treat several kinds of cancer such as bones, muscles, kidneys, uterus, testicles, joints, and soft tissues. The provided injection is also used to treat solid tumors.

Precautions for Dactinomycin Injection

Before taking Dactinomycin Injection, tell your doctor if you have recently received radiation therapy for Wilms tumor.

Contraindications for Dactinomycin Injection

Administration of Dactinomycin injection should be avoided if you are allergic to it or have recently chickenpox or herpes zoster (shingles) infection.Use of this medication should be strictly avoided in pregnant women and nursing mothers as it may harm the unborn baby and nursing baby as well.

Side Effects of Dactinomycin Injection

Seek medical attention if you experience any of side effects such as vomiting, malaise, fatigue, cheilitis, nausea, dysphagia, hyperpigmentation of previously radiated areas, bone marrow depression gastric ulceration, hepatitis, hepatomegaly, abnormal liver function, alopecia, skin eruption.
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