Di Sodium Pamidronate Injections

Di Sodium Pamidronate Injections

Having enormous experience in this domain, we are successfully engrossed in providing high grade Di Sodium Pamidronate Injection. This injection is formulated with the help of our experienced professionals by utilizing advanced methodology at our well-maintained premises. Known for precise composition, it is injected into patient’s vein for treating high calcium levels or hypercalcemia as well as bone problems. We provide the offered Di Sodium Pamidronate Injection in hygienic packaging at cost effective prices.

Key points:

 

Quick results Enhanced shelf life Highly effective Balanced chemical composition 

 

Di Sodium Pamidronate Injection

It is a bone resorption inhibitor.

Composition :

15mg, 30mg, 60mg, 90mg

Indications :

Hypercalcaemia of malignancy, Paget's disease, Osteolytic bone metastasis of breast cancer, and Osteolytic lesions of multiple myeloma.

Contraindications :

Patients with clinically significant hypersensitivity to pamidronate or other biphosphonates.

Safety Profile :

Standard hypercalcemia related metabolic parameters such as serum levels of calcium, phosphate, magnesium and potassium should be carefully monitored.

Adverse Effects :

Fluid overload, generalized pain, Hypertension, abdominal pain, anorexia, constipation, nausea, vomiting, urinary tract infection, bone pain, anaemia, hypophosphatemia.

Dosage :

Paget's disease - 60mg by slow iv infusion at a rate of 15mg/hour, optimal dosing regimen adjusted individually according to response.
Hypercalcaemia of malignancy : Slow iv infusion at a rate of 60 mg/hour dose adjusted according to initial plasma calcium concentration : 30mg when plasma calcium is below 3.00 mmol/L, 30-60mg when plasma calcium 3.0-3.5 mmol/L, 60-90 mg when plasma calcium 3.5-40 mmol/L, 90 mg when plasma calcium is above 4.0 mmol/L Repeat dose every 2-3 weeks as necessary.
Bone metastasIs : Slow iv infusion 2 hours in breast cancer, 4 hours in multiple myeloma, 90mg every 3-4 weeks.

Purity :

Not less than 99%.




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