Dacarbazine Injection is a potent anti-cancerous formulation. Dacarbazine belongs to the group of medicines called alkylating agents. It slows down and stops the growth of cancer cells in body. The offered anti-cancerous injection is used to treat cancer of the lymph system and malignant melanoma (a type of skin cancer).
Before starting the treatment with Dacarbazine, you should discuss with your doctor about medical history, ongoing medications, any allergies, pregnancy or planning to become pregnant or breastfeeding and any other noteworthy facts about your health.
Dacarbazine Injection is contraindicated in patients who are allergic to Dacarbazine or to any of the ingredients of the medication and with pre-existing or existing bone marrow suppression.
Seek immediate medical advice from the doctor if you experience side effects like blurred vision, confusion seizures, and sores in the mouth and on the lips. It is advisable to stop taking medication if one observes these side effects - chest pain, black or tarry stool, or blood in the urine, cough or hoarseness with fever or chills, face swelling, lower back or side pain with fever or chills, pain, redness, or swelling at the injection site, difficulty in urination with fever or chills, shortness of breath and stomach pain.
We come up in the market with an objective to cater diverse needs of clients by offering the best quality Oxaliplatin Injection. The provided product is injected into patients body who are suffering from colon and rectal cancer. Under the stringent observation of dexterous professionals, this injection is formulated with the use of sophisticated methodology. Prior to packaging procedure, the offered Oxaliplatin Injection is rigorously checked on quality parameters to ensure its high effectiveness.
Each vial contains:- Oxaliplatinâ€¦.. 2 mg per ml
Pack Size:-25ml , 50 ml
Oxaliplatin is a neoplastic drug used in metastatic colorectal cancer where fluropyrimidines therapy or alone chemotherapy have failed, also used along with fluropyrimidines.
|Composition :|| Each vial contains:
Each vial contains:
Oxaliplatin -------------------25mg, 50mg, 100mg
Water for injection -----------q.s.
|Indications :|| oxaliplatin used in combination with infusional 5-fluorouracil/leucovorin, is indicated for:
â€¢ adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor.
treatment of advanced colorectal cancer.
|Contraindications :|| Oxaliplatin should not be administered to patients with a history of known allergy to oxaliplatin or other platinum compounds .
|Adverse Effects :||Serious adverse reactions including anaphylaxis and allergic reactions, neuropathy,pulmonary toxicities and hepatotoxicities can occur..|
|Dosage :|| oxaliplatin 85 mg/mÂ² intravenous infusion in 250-500 mL 5% Dextrose injection, USP and leucovorin 200 mg/mÂ² intravenous infusion in 5% Dextrose Injection, USP both given over 120 minutes at the same time in separate bags using a Y-line, followed by 5-fluorouracil 400 mg/mÂ² intravenous bolus given over 2-4 minutes, followed by 5-fluorouracil 600 mg/mÂ² intravenous infusion in 500 mL 5% Dextrose Injection, USP (recommended) as a 22-hour continuous infusion.
Day 2: Leucovorin 200 mg/mÂ² intravenous infusion over 120 minutes, followed by 5-fluorouracil 400 mg/mÂ² intravenous bolus given over 2-4 minutes, followed by 5-fluorouracil 600 mg/mÂ² intravenous infusion in 500 mL 5% Dextrose Injection, USP (recommended) as a 22-hour continuous infusion.
|Pharmacological action :|| Oxaliplatin is a neoplastic drug used in metastatic colorectal cancer where fluropyrimidines therapy or alone chemotherapy have failed, also used along with fluropyrimidines.
Precautions : Oxaliplatin may rarely cause a severe (possibly fatal) allergic reaction within minutes after a dose. Tell your doctor immediately if you develop any signs of an allergic reaction (e.g., rash, itching, swelling, trouble breathing, dizziness)..
|Drug interaction:||No pharmacokinetic interaction between 85 mg/mÂ² of Oxaliplatin and infusional 5-fluorouracil has been observed in patients treated every 2 weeks, but increases of 5-fluorouracil plasma concentrations by approximately 20% have been observed with doses of 130 mg/mÂ² of Oxaliplatin administered every 3 weeks. In vitro, platinum was not displaced from plasma proteins by the following medications: erythromycin, salicylate, sodium valproate, granisetron, and paclitaxel. In vitro, oxaliplatin is not metabolized by, nor does it inhibit, human cytochrome P450 isoenzymes. No P450-mediated drug-drug interactions are therefore anticipated in patients..|
|Precautions:||Oxaliplatin may rarely cause a severe (possibly fatal) allergic reaction within minutes after a dose.|
With the aid of our adroit professionals, we have been involved in providing quality tested Cytosine Arabinoside Injections. Cytosine Arabinoside injection is a type of chemotherapy drug called as anti metabolite. It is used in the treatment of acute myeloid leukemia, chronic myelogenous leukemia and non-Hodgkin's lymphoma. It interferes with DNA synthesis and stops the growth of cancer cells.
Before the use of Cytosine Arabinoside, tell your doctor about your current list of pre-existing diseases, ongoing medications or any other health care products (e.g. vitamins, herbal supplements ), allergies and current health conditions (e.g. pregnancy, upcoming surgery etc).
Use of this medicine is contraindicated in children, pregnant ladies or planning to become pregnant, existing bone marrow suppression, gout, kidney problems and liver problems. It is important to discuss as certain health conditions may make you more vulnerable to the side-effects of the drug.
Seek medical attention if you observe any of side-effects like bone marrow depression, vomiting, nausea, decreased appetite, rash and eye irritation etc.
Fludarabine injection is indicated to treat a type of leukemia. It acts effectively on Chronic Lymphocytic Leukemia (CLL a type of cancer of the white blood cells) in adults who have already been treated with an alkylating agent like bendamustin but did not get better.
Fludarabine injection belongs to the category of medications called antimetabolites. It acts by inhibiting DNA synthesis and stops the growth of cancer cells.
Fludarabine injection is also sometimes used to cure non-Hodgkin's lymphoma (NHL, cancer that starts in white blood cells which are part of body’s immune system) and mycosis fungoides (this form of cancer spreads gradually and some of the body's white blood cells become malignant).
Before taking medication tell your doctor if you have any kind of allergies such as to foods, dyes, preservatives or animals. Also tell if you ever had any allergic reaction to this medicine.
Fludarabine is contraindicated in those are hypersensitive to this drug or its components. In addition, use of this medicine should be avoided if you taking pentostatin.
Get emergency medical attention if you experience side effects such as fever, chills, sore throat, flu symptoms, difficulty in breathing, hives, swelling of your face, lips, tongue or throat, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, unusual weakness, pale or yellowed skin, dark colored urine.