Dacarbazine Injection- Anticancer Cure

Dacarbazine Injection- Anticancer Cure

Dacarbazine Injection

Dacarbazine Injection is a potent anti-cancerous formulation. Dacarbazine belongs to the group of medicines called alkylating agents. It slows down and stops the growth of cancer cells in body. The offered anti-cancerous injection is used to treat cancer of the lymph system and malignant melanoma (a type of skin cancer).

Precautions

Before starting the treatment with Dacarbazine, you should discuss with your doctor about medical history, ongoing medications, any allergies, pregnancy or planning to become pregnant or breastfeeding and any other noteworthy facts about your health.

Contraindications

Dacarbazine Injection is contraindicated in patients who are allergic to Dacarbazine or to any of the ingredients of the medication and with pre-existing or existing bone marrow suppression.

Side Effects

Seek immediate medical advice from the doctor if you experience side effects like blurred vision, confusion seizures, and sores in the mouth and on the lips. It is advisable to stop taking medication if one observes these side effects - chest pain, black or tarry stool, or blood in the urine, cough or hoarseness with fever or chills, face swelling, lower back or side pain with fever or chills, pain, redness, or swelling at the injection site, difficulty in urination with fever or chills, shortness of breath and stomach pain.




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L-Asparaginase Injection

L-Asparaginase Injection

L-Asparaginase Injection

Asparaginase belongs to a class of medicines called as Antineoplastic. Antineoplastics or anticancer drugs prevent or inhibit the abnormal maturation and proliferation of tissue. It is used to treat a certain type of blood cancer called acute lymphoblastic leukemia (ALL). In addition, it is also used in some mast cell tumor protocols.

Precautions of L-Asparaginase Injection

Before starting treatment with L-Asparaginase Injection, it is important to tell your doctor about your ongoing medications or non prescribed medicines (vitamins, herbal remedies). While taking this medicine, don’t take any kind of immunization or vaccination without your doctor's approval. In addition, inform your health care professional if you are pregnant or planning for pregnancy.

Contraindications for L-Asparaginase Injection

This medicine is contraindicated if one has a history of pancreatitis (inflammation of the pancreas), diabetes, kidney disease caused by increased uric acid in the body, gout, anemia, acute hemorrhage, azotemia, high amount of bilirubin in the blood, brain-capillary leak syndrome.

Side effects of L-Asparaginase Injection

Seek medical attention, if you have any signs of an allergic reactions like hives, difficulty in breathing, swelling of your face, lips, tongue, or throat, severe pain in your upper stomach radiating to back, nausea and vomiting, fast heart rate, easy bruising or bleeding, unusual weakness etc.

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Best anticancer cure in India - Doxorubicin Injectables

Best anticancer cure in India - Doxorubicin Injectables

Relying on our transparent business practices, we are engaged in providing quality checked Doxorubicin Injection. By incorporating advanced methodology, this injection is formulated with the help of skilled professionals using high grade chemicals. Demanded in hospitals, clinics and health care centers, the provided injection is highly effective for curing bladder, blood, bone, stomach, testicle and ovary cancer. In addition, we provide this Doxorubicin Injection in hygienic packaging at the most economical prices.

Key points:

Balanced chemical composition No side effects Free from adulteration Quick results

 

Category: Anti neo-plastic 
Each vial contains:- Doxorubicin¦.. 10mg and 50mg
Quality Specification: Chromatographic Purity: NLT 99%

It is a antitumour antibiotic and finds a useful application in acute leukemia & in many solid tumours. Doxorubicin is capable of cusing breaks in DNA strands and have mutagenic and carcinogenic potential. Maximum action is exerted at S phase, but toxicity is usually exhibited in G2 phase.


Composition :

Each vial contains: 
Doxorubicin Hydrochloride.10mg, 50mg, 100mg 
Lactose Monohydrate 50mg, 200mg, 500mg

Indications :

Doxorubicin has been used successfully to produce regression in disseminated neoplastic conditions such as acute lymphoblastic leukemia, acute myeloblasticleukemia, Wilms' tumor, neuroblastoma, soft tissue and bone sarcomas, breast carcinoma, ovarian carcinoma, transitional cell bladder carcinoma, thyroid carcinoma, gastric carcinoma, Hodgkin's disease, malignant lymphoma and bronchogenic carcinoma in which the small cell histologic type is the most responsive compared to other cell types.

Contraindications :

In patients with history of hypersensitivity to the drug, pregnancy, location.

Pharmacological action:

: It is a antitumour antibiotic and finds a useful application in acute leukemia & in many solid tumours. Doxorubicin is capable of cusing breaks in DNA strands and have mutagenic and carcinogenic potential. Maximum action is exerted at S phase, but toxicity is usually exhibited in G2 phase

Adverse Effects :

: Cardiotoxicity, alopecia, Bone marrow depression, alopecia, cardiomyopathy, stomatitis, vomiting and local tissue damage.

Dosage :

1.2-2.4 mg/kg body wt or 60-75 mg/sq metre of body surface given as a single dose every 3 week by slow i.v. inj. Doxorubicin has been used concurrently with other approved chemotherapeutic agents. Evidence is available that in some types of neoplastic disease combination chemotherapy is superior to single agents. The benefits and risks of such therapy continue to be elucidated. When used in combination with other chemotherapy drugs, the most commonly used dosage of doxorubicin is 40 to 60 mg/m2 given as a single intravenous injection every 21 to 28 days.

Drug interaction:

Doxorubicin is extensively metabolized by the liver. Changes in hepatic function induced by concomitant therapies may affect doxorubicin metabolism, pharmacokinetics, therapeutic efficacy, and/or toxicity. Toxicities associated with doxorubicin, especially hematologic and gastrointestinal events, may be increased when doxorubicin is used in combination with other cytotoxic drugs.

Precautions:

ECG changes, arrhythmias, hypotension, or be delayed congestive heart failure.Doxorubicin may cause heart problems, including possibly fatal heart failure. Heart problems may occur durin doxorubicin therapy or months to years after receiving this medication


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Epirubicin Injection

Epirubicin Injection

Epirubicin Injection

Epirubicin injection has strong anti tumor action by interfering with the synthesis and function of DNA. The given injection is used to treat cancers of breast, lungs, ovaries, lymph system and stomach. Epirubicin is an antineoplastic in the anthracycline class which prevents abnormal growth of tissues.

Precautions for Epirubicin Injection

This injection is to be administered only under the supervision of your doctor. Epirubicin should be injected slowly into a vein. Do not inject into a muscle or under the skin. If this medication by coincidence leaks into the skin/muscle around the injection site, it may cause serious damage. Tell your doctor without delay if you observe redness, pain or swelling at or near the injection site.

Contraindications for Epirubicin Injection

Use of this medicine should be avoided in those are allergic to epirubicin or to any of the ingredients of the medication, allergic to other anthracycline-type medications like doxorubicin, breast-feeding, recent heart attack, heart failure, irregular heart rhythm, severe heart disease, severe liver impairment.

Pharmacological Action of

Epirubicin forms a complex with DNA by intercalation of its planar rings between nucleotide base pairs, with consequent inhibition of nucleic acid (DNA and RNA) and protein synthesis.Such intercalation triggers DNA cleavage by topoisomerase II, resulting in cytocidal activity. Epirubicin also inhibits DNA helicase activity, preventing the enzymatic separation of double-stranded DNA and interfering with replication and transcription

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