Amphotericin-B Injection

Amphotericin-B Injection

Amphotericin B is an antifungal medicine and used to treat potentially fatal fungal infections. It acts by stopping the growth of fungi. This topical medication is indicated in oral, vaginal and cutaneous candidiasis and otomycosis.

Precautions

Discuss with your doctor if you have previously experienced any unusual allergic reaction to this medicine or any other medicine. Also tell your doctor if you have any other types of allergies for food, foods, dyes, preservatives, or animals.

Contraindications

Use of this medication is contraindicated if you have systemic mastocytosis, low amount of magnesium and potassium in the blood and kidney disease which has impaired kidney functions.

In addition, this medicine should not be taken by the people who have any allergic reaction to Amphotericin B and Rotavirus Vaccine.

Side effects

Check with your doctor immediately if you experience any of following side effects such as

More common side effects associated with intravenous injection
  • Headache
  • Fever and chills
  • Increased or decreased urination
  • Irregular heartbeat
  • Muscle cramps or pain
  • Nausea
  • Vomiting
  • Pain at the place of injection
  • Unusual tiredness or weakness
Less common or rare side effects associated with intravenous injection
  • Sore throat and fever
  • Numbness, tingling, pain, or weakness in hands or feet
  • Shortness of breath, troubled breathing, wheezing, or tightness in chest
  • Skin rash or itching
  • Blurred or double vision
  • Convulsions (seizures)
  • Unusual bleeding or bruising
Side effects associated with spinal injection
  • Blurred vision or any change in vision
  • Difficulty in urination
  • Numbness, tingling, pain, or weakness



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Contraindications

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Key Points:

Antibiotic Highly effective Known for purity Inhibits the growth of bacteria

 

 

 

Each vial contains:- Meropenam - 500 mg and 1 gm
Quality Specification: Chromatographic Purity - NLT 99.5%%


Pack Size: vial

Composition :

125mg, 250mg,500mg,1gm

MEROPENAM :-

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Indication :

Pneumonias, gynecological infections, skin and soft structure infections, meningitis, septicaemia and adult febrile neutropenia.

Dosage and administrations :-

Administered as an intravenous injection over approkximately 5 minutes or by intravenous infusion over approximately 15-30 minutes with compatible infusion (50-200ml) fluid.

Adult :-

Pneumonias, UTI, skin and skin structure infections :500mg 8hourly. Nosocomial Pneumonias, peritonitis, septicemia: 1g every 8hours. Meningitis : 2g every 8 hours

Contra-Indications :-

Hypersensitivity to ingredients. Hypersensitivity to pencilins or other beta-lactam antibiotics.

Warning :


Special Precautions :-


Paediatrics :-

Safety is not established in patient with neutropenia or primary/secondary immuno deficiency. Safety is not established in infants under 3 months of age.

Pregnancy :-

Safety is not established

Lactation :-

Safety is not established.

Elderly :-

Safe for elderly with normal renal functions.

Side–effects :-

Serious adverse effects are rare. Local IV injection site reaction, site reaction and neutrophilia. Headache, paresthesia, convulsions, oral and vaginal candidiasis.

Drug Interactions :-

Nephrotoxic drugs, probenocid, sodium valproate etc.


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